Oral bioavailability of chondroitin sulfate (Condrosulf®) and its constituents in healthy male volunteers

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Poly-ion Complex of Chondroitin Sulfate and Spermine and Its Effect on Oral Chondroitin Sulfate Bioavailability.

Chondroitin sulfate (CS) has been accepted as an ingredient in health foods for the treatment of symptoms related to arthritis and cartilage repair. However, CS is poorly absorbed through the gastrointestinal tract because of its high negative electric charges and molecular weight (MW). In this study, poly-ion complex (PIC) formation was found in aqueous solutions through electrostatic interact...

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ژورنال

عنوان ژورنال: Osteoarthritis and Cartilage

سال: 2002

ISSN: 1063-4584

DOI: 10.1053/joca.2002.0824